Research Article
Alteration in the serum levels of interleukin-6 and interleukin-15 in the patients of knee osteoarthritis
Author(s): Aman Chauhan*, Manju Bala, Rajesh Rohilla and Rooma Devi
Background: Osteoarthritis is the most common type of arthritis affecting mostly the weight bearing joints. Pro-inflammatory cytokines including IL-6 and IL-15 are predominately secreted by macrophages and other cells and they are involved in up regulation of inflammatory response. IL-6 and IL-15 may induce expression of proteolytic enzymes which cause cartilage damage and in turn osteoarthritis. This study is designed to evaluate the serum levels of IL-6 and IL-15 in the patients of knee OA and their possible role in its pathogenesis.
Aim: To evaluate the role of IL-6 and IL-15 in the patients of knee osteoarthritis.
Materials and methods: The present study was conducted in the department of biochemistry in collaboration with department of orthopedics from May 2018 till July 2020. Forty patients with knee osteoart.. Read More»
DOI:
10.37532/puljcgg.23.6(1).1-4
