Perspective
Bacterial infections in lupus
Author(s): Anne Williams*
In individuals with systemic lupus erythematosus (lupus), bacterial infections of the lungs, skin, circulation, and other organs are prevalent, and they are often more severe and invasive than similar infections in healthy people. Using both human patient samples and animal models of lupus, a number of research have looked at changes in bacterial abundance in lupus patients, infection rates, and the effect of certain bacterial species on disease development. The purpose of this review is to summarize human and mouse studies that describe changes in the bacterial microbiome in lupus, the role of a leaky gut in stimulating inflammation, the identification of specific bacterial species associated with lupus, and the potential roles of common bacterial infections in promoting lupus progression. The data was gathered by searching the PubMed database for papers about bacterial infections in.. Read More»
DOI:
10.37532/puljcmid.2022.5(1).01-02