Department of propaedeutics of internal diseases, State Pediatric Medical University, Saint-Petersburg, Russia

Publications

• Original Article   
  Cardiomyopathy in patients with Marfan syndrome and marfanoid habitus
  Author(s): Ekaterina Luneva*, Eduard Malev, Alexandra Korshunova, Svetlana Reeva, Eugeniy Timofeev and Eduard Zemtsovsky
  
  OBJECTIVES: The term “Marfan cardiomyopathy” is used to indicate changes in left ventricular function in the absence of significant valvular pathology in Marfan syndrome. It is still unknown if there are any changes in cardiac function in patients with similar connective tissue abnormality such as marfanoid habitus. METHODS: In the study were included 98 persons - 8 patients with Marfan syndrome, 24 with marfanoid habitus and 66 healthy subjects. Echocardiography was performed to all patients. Speckle tracking echocardiography was used to assess the left ventricular deformation indices. Concentrations of transforming growth factor-β1 and -β2 in serum were determined by enzyme-linked immunosorbent assay. RESULTS:.. Read More»
  DOI: 10.4172/2368-0512.1000082

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