Commentary
The effect of advanced aging on adrenal hormone levels on sexual
dimorphism
Author(s): James Adam*
Ageing and adrenal function have attracted a lot of attention recently. The plasma levels of cortisol, De-hydropiandrosterone (DHEA), DHEAsulfate (DHEAS), and the molar ratio of cortisol/DHEAS in 50 years to 80 years old community-dwelling people are examined in this crosssectional research. In samples collected between 7:30 hours to 11:00 hours from 857 males and 735 postmenopausal women who did not use steroid hormones, plasma hormone levels were measured. ANOVA with two factors (gender and age) was used to compare hormone levels in 10- year age groups. Overall, women had 40% lower levels of DHEA and DHEAS (collectively DHEA(S)) and 10% higher levels of cortisol than males, resulting in a 1.7-fold higher cortisol/DHEAS molar ratio for women (both, P , 0.001). With age, both men and women's cortisol levels gradually increased (20% overall) (both, P, 0.01). While both men and wome.. Read More»
DOI:
10.37532/puljeds.22.6.3:18-19
+443308089004
