Perspective
Arsenic: Cellular physiology of biomolecular condensates
Author(s): Jennifer Stewart*
For a reasonably long period, it has been recognized that cells can contain organelles without membranes. Stress granules, processing bodies, and PML-NBs have all undergone extensive arsenic-related research among the membrane-less organelles. Recently, it has been demonstrated that the membrane-less organelles that concentrate biomolecules (proteins, nucleic acids) can self-organize through phase separation/transition. These biomolecular condensates (membrane-less organelles) can boost a particular reaction’s efficiency locally. Since the membrane-dependent certain compartmentalization has long been known to explain highly ordered biochemical complexes in cells, the biomolecular condensates have garnered enormous attention. In this brief review, we focus on how phase separation begins in each biomolecular condensate that arsenic may be present. We consider the suitability of th.. Read More»
DOI:
10.37532/pulject.2022.6(4);01
+447723598358
