Reviews
New pattern clinical study of adverse drug reaction to ART may lead to chase drug discovery in anti-retroviral drug towards zero adverse drug reaction
Author(s): Rahul Hajare*
ART drug is widely used Anti-HIV agents. Of these, molecular recognition in their molecular nucleus likes diarylpyrimidine, benzoxazinone, heterocyclic most present in ART. Apart from these, some hetero atom along with some special core group have been reported. They are effective and not very costly, though there are also possibilities of ART adverse reactions common with use of ART. Cross reactivity between for example Etravirine and Rilpivirine, earlier reported may exceed 30%. Common adverse drug reaction for highly protein bound ART, includes hypersensitivity reactions were characterized by rash, fever and sometimes organ involvement including, but not limited to, severe rash or rash accompanied by fever, general malaise, fatigue, muscle or joint aches, blisters, oral lesions, conjunctivitis, hepatitis and eosinophilia. indices were included. Adverse drug reactions caused by drug.. Read More»
DOI:
10.4172/2529-797X.1000018