Opinion
Regulation of the production of fungal cell walls post-transcriptionally
Author(s): Rebecca James*
By coating immunogenic cell wall components like β-glucan with harmless coverings like mannoproteins and α-glucan that the host is less likely to recognize, pathogenic fungi conceal themselves from their hosts. The success of efforts to comprehend how such processes are controlled has varied. Studies often concentrate on comprehending how fungi respond transcriptionally to either their reservoir environment or the host. However, because of the levels of post-transcriptional and posttranslational regulation that take place within a cell, such techniques do not completely address this study subject. Although the effects of posttranscriptional and post-translational regulation have been extensively studied in mammals, we know less about these mechanisms in the kingdom of fungi. Mutations in RNA-binding proteins, such as Candida albicans Slr1 and Ssd1, impact the structure of t.. Read More»
DOI:
10.37532/ puljcmid.2022.5(4).34-35
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