Original Article
Research investigating antioxidation of astaxanthin extracted from Haematoccus pluvialis in mice
Author(s): Shaolei Yu*, Weichun Du and Qianwen Li
Objective: To evaluate the antioxidative effect of astaxanthin extracted from Haematoccus pluvialis in mice. Methods: Fifty mice were randomly divided into five groups (high-dose [astaxanthin 4.0 mg/kg]; medium dose [astaxanthin 2.0 mg/kg]; low dose [astaxanthin 1.0 mg/kg]; model control; and blank control). The experimental substance was administered every day. Mice in the model group and the control group received an equal volume of vegetable oil for 30 days. After 30 days, blood antioxidant enzyme activity was measured in tail blood. Except for the blank control group, the other groups were exposed to 8 Gy 60Coγ irradiation. On the fourth day after irradiation, all animals were euthanized and liver tissue was tested for malondialdehyde, superoxide dismutase and glutathione peroxidase activity levels. Results : Superoxide dismutase levels in all th.. Read More»
DOI:
10.4172/2529-797X.1000011