Original Article
Evaluation of serum thiol/disulfide homeostasis in pediatric patients diagnosed with vitamin B12 deficiency
Author(s): Sibel Tekgündüz, Huseyin Avni Solgun*, Sahin Gulseren and Erel Ozcan
Background: It may not be easy to recognize vitamin B12 deficiency by both clinical and laboratory tests. In its deficiency, it may be asymptomatic or cause life-threatening symptoms such as severe myelopathy and pancytopenia. The first examination required for the diagnosis of vitamin B12 deficiency is usually the measurement of serum vitamin B12 level. Due to the limitations of serum vitamin B12 measurement in detecting vitamin B12 deficiency, methyl malonic acid, homocysteine, or both will be measured in patients with clinical findings consistent with deficiency.
Materials and Methods: Our study was planned prospectively as a casecontrol study. Forty-five (Female: 15, Male: 30) patients who had Vitamin B12 deficiency between May 2019 and August 2019, and 40 healthy (Female: 25, Male: 15) who had normal vitamin B12 levels for control purpo.. Read More»
DOI:
10.37532/puljphcm.2022.5(1).1-4
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