Perspective
Neospora caninum infection of the nervous system,
kynurenine pathway, and the parasitic pathway
Author(s): Steve Raul*
Neuroinflammation is a prevalent trait in virtually all neurological illnesses, making it one of the most researched areas in neuroscience. Although neuroinflammation's primary job is to defend the nervous system from an injury, the complicated and sequential response of activated glial cells can cause neurological damage. The inflammatory response can be neuroprotective, neurotoxic, or both depending on the kind of glial cell and the period after the injury. During neuroinflammation, numerous pathways are engaged, and several bioactive intermediates are produced. The kynurenine pathway, which catabolizes tryptophan and is involved in immunological control, neuroprotection, and neurotoxicity, is one of the most frequent. Various models have been utilised to investigate the kynurenine pathway metabolites' roles in the development and maintenance of inflammatory processes genera.. Read More»
DOI:
10.37532/pulnp.2022.2(2).25-27
+447723598358
