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Bone Marrow Transplantation

A bone marrow transplant is a procedure by which to substitute damaged or killed bone marrow with healthy bone marrow stem cells. Bone marrow is the delicate and fat tissue within bones. The blood cells are made from bone marrow. Bone marrow stem cells are immature cells that give rise to all of the various blood cells. Until transplantation it can be given chemotherapy, radiation, or both. It can take two different forms:

Ablative (myeloablative) medication — To destroy all cells, high-dose chemotherapy, radiation, or both are administered. It also kills the remaining healthy bone marrow, allowing new stem cells to form in the bone marrow.

Reduced intensity treatment, also called a mini transplant — Lower doses of chemotherapy and radiation are administered before a transplant. It allows the transplantation of the elderly, and those with certain health problems.

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