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Glycoprotein

Glycoproteins are contain oligosaccharide chains covalently attached to amino acid side-chains. The carbohydrate is attached to the protein during a cotranslational or posttranslational modification. This process is understood as glycosylation. they are doing many important jobs for the body, like helping the immune, digestive, and reproductive systems. Glycoproteins are proteins that contain covalently attached sugar residues. The hydrophilic and polar characteristics of sugars may dramatically change the chemical characteristics of the protein to which they're attached. Examples. One example of glycoproteins found within the body is mucins, which are secreted within the mucus of the respiratory and digestive tracts. P-glycoprotein is one among the drug transporters that determine the uptake and efflux of a variety of medicine. P-glycoprotein features a modest role in drug elimination. it's expressed within the luminal membrane of proximal tubule cells within the kidneys. P-glycoprotein pumps drugs into the urine.P-glycoprotein is that the most vital drug transporter for reducing the entry of medicine into the central systema nervosum. The over-the-counter antidiarrhoeal medication loperamide may be a potent opiate but doesn't have opioid effects on the central systema nervosum at usual doses. this is often because P-glycoprotein prevents transport across the barrier.

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