Pulsus
Pulsus health tech
44 2033180199
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Awards Nomination
Flyer image
25+ Million Website Visitors

Neurotoxicity

The term neurotoxicity refers to interrupt to the brain or peripheral system nervous caused by exposure to natural or semisynthetic nephrotoxic substances. These toxins will alter the activity of the system nervosas in ways during which will disrupt or kill nerves. Nerves square measure essential for sending and process info within the brain, additionally as different areas of the systema nervosas. because of their high rate , neurons square measure at the only risk of injury caused by neurotoxins. this will be followed, so as of risk, by oligodendrocytes, astrocytes, glia and capillary epithelium cells. depending on a neurotoxin’s chemical profile, it'll cause harm to sure components or specific cellular components of the nervous system . Non-polar substances square measure tons of soluble in lipids and might so access the tissue tons of simply than polar compounds, that square measure less soluble in lipids. The body’s response to neurotoxins is influenced by factors a bit like the neurochemical affected, cellular membrane integrity then the presence of detoxifying mechanisms.The presence of neurocognitive deficits alone isn't typically thought-about enough proof of neurotoxicity, as several substances could impair neurocognitive performance while not resulting in the death of neurons. This might be due to the dissent of the substance, with the impairment and neurocognitive deficits being temporary, and breakdown once the substance is eliminated from the body. In some cases the extent or exposure-time is additionally important, with some substances solely becoming toxin in sure doses or time periods. variety of the foremost common present brain toxins that end in neurotoxicity as a results of excessive drug use square measure beta amyloid (Aβ), glutamate, dopamine, and O radicals. once gift in high concentrations, they'll end in neurotoxicity and death (apoptosis). variety of the symptoms that result from necrobiosis embrace loss of control, psychological feature deterioration and involuntary system nervous pathology. additionally , neurotoxicity has been found to be a big reason behind neurodegenerative diseases like Alzheimer's disease

High Impact List of Articles
Conference Proceedings

Relevant Topics in Pharmaceutical Sciences

 
Google Scholar citation report
Citations : 40

Clinical Pharmacology and Toxicology Research received 40 citations as per Google Scholar report

Flyer image

Indexed In

Read More
pulsus-health-tech
Top