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Polyamines

Polyamines: Polyamines are polycations that interact with molecules with negative charges, such as DNA , RNA and proteins. They play multiple roles in cell growth , proliferation and survival. Changes in polyamine levels were linked to ageing and disease. A polyamine is an compound having quite two amino groups. Alkyl polyamines occur naturally but also are synthetic. Alkylpolyamines are colorless, hygroscopic, and water-soluble. Near neutral pH, they exist because the ammonium derivatives. Most aromatic polyamines are crystalline solids at temperature . Low-molecular-weight linear polyamines are found altogether sorts of life. The principal examples are the triamine and tetraamine spermidine and spermine. they're structurally and biosynthetically associated with the diamines putrescine and cadaverine. Polyamine metabolism is regulated by the activity of the enzyme ornithine decarboxylase (ODC). Polyamines are found in high concentrations within the mammalian brain.

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