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Proteomic Technology

Proteomics is the protein equivalent of genomics and has captured the imagination of biomolecular Proteomics is that the protein equivalent of genomics and has captured the imagination of biomolecular scientists worldwide. It encompasses a broad range of technologies aimed toward determining the identity and quantity of expressed proteins in cells, their three-dimensional structure and interaction partners. within the postgenomic era, proteomics may be a rapidly growing field of research that's becoming increasingly important. for instance , it's extensively applied to the study of proteins involved in carcinogenesis, also on discover biomarkers for clinical use. Disease markers are widely used for screening, diagnosis, staging, prognosis, monitoring response to treatment, and detection of recurrent diseases.As protein-protein interactions are the key to signal transduction to several regulatory events, a scientific classification of protein-protein interfaces may be a valuable resource for understanding the principles of molecular recognition and for modeling protein complexes. The question of how one protein regulates the activity of another by binding thereto requires an integration of structural, functional, and dynamic information. within the last decade, there are many improvements in protein separation techniques, including two-dimensional polyacrylamide gel electrophoresis (2-D PAGE), liquid chromatography (LC), isotope-coded affinity tag (ICAT) labeling, and so on. Much progress has also been recently achieved within the analysis of proteins from tryptic digests using mass

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