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Remyelination

Remyelination is the process to create new myelin sheaths on demyelinated axons by propagating oligodendrocyte precursor cells to form oligodendrocytes in the CNS. This process creates a thinner myelin sheath than normal, but it helps to shield the axon from further harm, from overall degeneration, and proves to strengthen conductance once again. The thinner myelin not only restores protection of the axon from degradation, but also restores a faster conduction velocity. The conduction velocity, however, isn't as strong as naturally myelinated axons and therefore the Nodes of Ranvier are inclined to be wider which results in less coverage in the axon by myelin than what is natural. This is a process naturally regulated in the body and tends to be very useful in a healthy CNS. The processes hidden in the remyelination are under review in the hope of finding treatments for Demyelinating diseases, such as multiple sclerosis. It is initiated and regulated by wide variety of factors enveloping lesion sites which control the migration and separation of Oligodendrocyte Precursor Cells.

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