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Sara Bahram Miran
Tishk International University, Iraq
ScientificTracks Abstracts: Nanotechnology Letters
Statement of the Problem: Some types of skin infections develop resistant to antibiotics. For this reason recently another approach has been developed for treatment of skin infections caused by multi-drug resistant bacteria with nanoparticles as a drug delivery. Using biosynthesis nanoparticles by exopolysaccharide of bacterial species. Methodology & Theoretical Orientation: isolation bacteria from saliva, green synthesis of metal nanoparticles from lipopolysaccharides of the bacteria, characterizations of the LPS and metal nanoparticles by UV-Vis Spectroscopy, ATR-FTIR, zeta potential, XRD, SEM, TEM, DLS, and ATM. In vitro application on of the nanoparticles against multi-drug bacterial species from the wound, in viva application of the prepared ointments with the nanoparticles for the treatment on different groups of rats using different ratios of nanoparticles, antibiotics and other commercial types of skin ointments. Findings: The exopolysaccharide can be used as a reducing agent for biosynthesizing of metal nanoparticles by exopolysaccharide and its effect on skin infection treatment was effective and with no toxicity. Conclusion & Significance: Depending on biosynthesis of nanoparticles can be a more helpful method than that of chemical and physical approaches and less cost effective since microbes found in nature and it’s a biological reduction process. Green gold nanoparticles production is a simple and environmentally beneficial way to avoid the problems that chemically produced gold nanoparticles bring in biomedical applications. A wide range of biological systems have been tested for their ability to act as reducing agents during the synthesis reaction.
A Medical Microbiologist, graduated from Hawler Medical University (BSc - 2017). Since then been employed at Tishk International University with a great experience of teaching skills for many years and laboratory diagnosis skills. After that started studying the MSc degree at Hawler Medical University and the MSc research project title is about (Antimicrobial Activities of gold nanoparticle biosynthesis by a bacterial species against multidrug resistance pathogens isolated from wound infection). Have worked in details for the synthesis of green nanoparticles with different approaches and used them as a drug delivery for the skin infection with multi-drug resistant bacteria.
