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Saad M Alshehri
King Saud University, Kingdom of Saudi Arabia
Posters & Accepted Abstracts: Nanotechnology Letters
The synthesis of copper nanoparticles (CuNPs) and nanocomposites contain CuNPs is a great challenge because of the redox-activity of copper and its ions. In the present study the hydrogel containing stable copper particles (HCuNPs) were successfully synthesized via in the polymer matrix using carboxymethyl cellulose (CMC), polyvinyl alcohol (PVA), and ethyleneglycol diglycidylether (EGDE) as the cross-linkers. The structural and morphological of HCuNPs were carried out from x-ray diffraction (XRD), electron microscopy (TEM), and energy-dispersive (EDX) and x-ray photoelectron spectroscopic (XPS) studies. TEM studies show the formation of spherical shaped particles of copper in the size range from 7 to 12 nm. The Viscoelastic properties of the hydrogel were measured and the storage modulus (G’) of the HCuNPs was found to be higher than that of loss modulus (G”). Moreover, the antibacterial activities of the hydrogel matrix and HCuNPs were measured against urinary tract infection (UTI) pathogens. The HCuNPs composites show higher antibacterial activities against the pathogenic microorganism (e.g. E. coli, K. pnemoniae, P. aeruginosa, P. vulgaris, S. aureus and P. mirabilis) compared to the corresponding hydrogel matrix. Keywords: Nanocomposite, copper nanoparticles, hydrogel, antibacterial activity, urinary tract infection.
