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Fei Liu, Bo Ma, Dandan Wang, Ruihan Zhong, Kaihao Lin, Shuo Li, Jie Zhang and Chaoyang Li
University of Science and Technology, China
ScientificTracks Abstracts: J Health Pol Manage
Background: High-Fow Nasal Cannula (HFNC) is a new type of oxygen therapy, but its application in surgery remains unclear, we tried to describe the application of HFNC in microlaryngoscopic surgery for the Chinese population. Methods: Nineteen adults, American Society of Anesthesiology class (ASA) 1–2 patients with body mass index<30 kg.m−2 underwent microlaryngoscopic surgery using HFNC for airway management. Outcomes included apnoea time, intraoperative oxygenation, carbon dioxide value, lactate value and the relationship between the duration of apnoea time and carbon dioxide levels. Results: A total of 19 patients underwent vocal cord tumor resection under a microlaryngoscope with HFNC as the sole method of ventilation. The mean age was 39.7 years old and the mean BMI was 23.9 kg.m−2 The mean apnea time was 21.5 min. The SpO2 of 18 patients remained above 90% and only 1 patient dropped to 88%. The average basal lactate and highest lactate value was 0.58 mmol. L−1 and 0.68 mmol.L−1. The diference between basal and highest lactate values was statistically signifcant (P<0.05). The average highest PaCO2 value was 79.4 mmHg. The PaCO2 increased by 1.68±0.12 mmHg every minute linearly. Conclusions: In the case series we have observed that HFNC would be safe and efective oxygenation and ventilation technique for selected Chinese patients undergoing non-laser microlaryngoscopic surgery within 30 min. The tubeless technology reduces the complications of tracheal intubation and jet ventilation and clears the surgical field of vision. Trial registration: Chinese Clinical Trial Registry (ChiCTR100049144). Keywords: High-fow nasal cannula, Transnasal humidifed rapid-insufation ventilatory exchange, Microlaryngoscopic surgery, Airway management, Apneic oxygenation
Recent publications :
1. Liu F, Gao C, Wang W, Hu J, Huang Z, Liang M, Li S. miR-137/ERRα axis mediates chemoresistance of nasopharyngeal carcinoma cells. J Cell Commun Signal. 2022 Mar;16(1):103-113.
2. Li S, Tang M, Zen N, Liang J, Xing X, Huang D, Liu F, Zhang X. LncRNA OIP5-AS1 Knockdown Targets miR-183-5p/GLUL Axis and Inhibits Cell Proliferation, Migration and Metastasis in Nasopharyngeal Carcinoma. Front Oncol. 2022 Jun 8;12:921929. doi: 10.3389/ fonc.2022.921929. PMID: 35756672; PMCID: PMC9214031.
3. Shuo Li,Peng He, Zhiwei Wang, Meng Liang, Wei Liao,Yili Huang,Mengshi Chi , Fei Liu,Nan Zen,Rongfei Su,Shulin Chen,Zhigang Liu&Haiyu Hong. RNAi-mediated knockdown of PFK1 decreases the invasive capability and metastasis of nasopharyngeal carcinoma cell line, CNE-2 [J]. Cell Cycle，2021;20(2):154-165
Liu Fei has worked and studied in the Department of otolaryngology for 10 years, laying a solid foundation for scientific research and accumulating rich clinical experience. In recent years, he is mainly engaged in the basic and clinical application research of nasopharyngeal carcinoma and laryngopharyngeal voice and he is good at microlaryngoscopic surgery.
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