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Pulsus Journal of Surgical Research

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Histopathological alterations of enterocytes in a patient co-infected with severe acute respiratory syndrome coronavirus 2 and mycobacterium tuberculosis. A case study

Webinar on Osteoporosis, Arthritis and Musculoskeletal Disorders

June 15, 2022 | Webinar

Rana S AL-Zaidi

King Faisal Hospital, Makkah, Kingdom of Saudi Arabia

ScientificTracks Abstracts: Pulsus J Surg Res

Abstract :

The ongoing novel coronavirus disease 2019 (COVID-19) is principally defined by its respiratory symptoms. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can affect the gastrointestinal tract (GIT) and although the pathogenesis of COVID-19 is understood, the exact pathological alterations following infection require further investigation. Here, we report our histopathological findings from a right hemicolectomy specimen from a patient coinfected with COVID-19 and Mycobacterium tuberculosis. Our observations showed that the novel SARS-CoV-2 can affect the GIT, causing epithelial injury and pathological alterations attributed to its ability to infect absorptive enterocytes by interacting with the angiotensin converting enzyme-2 (ACE2) receptor. These pathological findings are regarded as viral cytopathic changes and should be considered when evaluating gastrointestinal specimens from COVID-19-infected patients. Recent Publications 1) Rana al Zaidi. (2022), Eccrine Angiomatous Hamartoma With Arteriovenous Malformation: A Rare Entity Re-Explored; Cureus 14(3). 2) Rana al Zaidi, et.al.(2022), Peculiar Histopathological Alterations of Enterocytes in a Patient Co-Infected with Severe Acute Respiratory Syndrome Coronavirus 2 and Mycobacterium Tuberculosis: A Case Study, Gastrointest Dig Sys; 11:10. 3) Rana al Zaidi, Khalid M Alqurashi, Rani Alsairafi, Fahad M Alkhuzaei, et.al.(2021), Panniculitis Ossificans in Posterior Knee: An Unusual Presentation, Cureus 13(11).

Biography :

I'm a pathologist interested in bone and soft tissue pathology, GIT pathology, and hematopathology. I've published papers on topics related to GIT pathology, dermatopathology, soft tissue pathology, hematopathology, and neuropathology.

 
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Citations : 163

Pulsus Journal of Surgical Research received 163 citations as per Google Scholar report

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