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Sameh Elmahdy
Monsoura University School of Medicine, Egypt
Posters & Accepted Abstracts: J Mol & Cel Endocrinology
Redirect stem cell growth by Hsing single beiim 1.aser .in‹J apply the appropriate conditions to produce modified gene cnn attack cancer cells at .any stage. The stent cell which is axis of study is obtained from Stir day blastocysl (Embryonic siem cells › 'hich is Totipotent) and it is .also defined by the expression of several transcription factors and cell surface proteins. Thc transcription factors Oct-4, Nanog, and Sox2 form ihc core regulatory new ork iliai ensures flue suppression of genes ihiii lead to differentiation rind the maioieiiiince ol“ pluripotency. The cell surface a@igens most coiiinienly used to identify hES cells ate the glycolipids .stage specific embryonic antigen 3 hand 4 ;ind the keratan stilfiiie antigens Tra-1 -ñfl and Tr.i-1 -8 1. fly using human embryon ic stem cells to produce specialized cells .and hearing it with special technique , then applying the standared scaftold with special characters , the aim is to produce gene which c.an attack the growing cancer cells at any stage . The study put focus on replacing the P35g — site which control process of apoptosis . The study has iivo major dimensions, fir.st, is physical one " using the idea of reniotccontrol” as you can manage tliC acne behavior physically with changing special frequeiicie.‹.Second, chemical side, by using .‹ooie enhancers and inducers during the fiux of the modified gene.