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Aya Attia
Mansoura University School of Medicine, Egypt
Posters & Accepted Abstracts: J Hepato Gastroenterol
Redirect stem cell growth by using single beam laser and apply the appropriate conditions to produce modified gene can attack cancer cells at any stage. The stem cell which is axis of study is obtained from 5th day blastocyst (Embryonic stem cells which is Totipotent ) and it is also defined by the expression of several transcription factors and cell surface proteins. The transcription factors Oct-4, Nanog, and Sox2 form the core regulatory network that ensures the suppression of genes that lead to differentiation and the maintenance of pluripotency. The cell surface antigens most commonly used to identify hES cells are the glycolipids stage specific embryonic antigen 3 and 4 and the keratan sulfate antigens Tra-1-60 and Tra-1-81. By using human embryonic stem cells to produce specialized cells and treating it with special technique, then applying the standard scaffold with special characters , the aim is to produce gene which can attack the growing cancer cells at any stage . The study put focus on replacing the P35g – site which control process of apoptosis . The study has two major dimensions, first, is physical one " using the idea of remote control" as you can manage the gene behavior physically with changing special frequencies. Second, chemical side, by using some enhancers and inducers during the flux of the modified gene.
