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ALS is a progressive condition, it deteriorates with time. It has an impact on the spinal cord and brain nerves that regulate your muscles. It becomes more difficult for you to walk, talk, eat, and breathe as your muscles become weaker. Until all of the clinical characteristics are present, it may initially be challenging to confirm the diagnosis.The sensory or autonomic—are involved. Although imaging is frequently required to rule out structural pathology that mimics MND, the diagnosis is clinical.