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Anatomical anomalies refer to deviations from the typical structure of organs and tissues in the human body. These variations can range from minor deviations to significant malformations, affecting various systems and presenting diverse clinical implications. This review aims to provide a comprehensive overview of anatomical anomalies, including their classification based on embryological origins, genetic influences, and environmental factors. The clinical significance of these anomalies in diagnosis, treatment planning, and surgical interventions will be discussed, emphasizing their impact on patient management and outcomes.