Approaches to multi-target treatment of Parkinson’s and Alzheimer’s disease

Parkinson's Disease (PD), often known as Parkinson's disease, is a chronic degenerative condition of the central nervous system that primarily affects the motor system. Non-motor symptoms normally appear gradually, and as the disease progresses, they become more prevalent. Tremors, stiffness, slowness of movement, and trouble walking are the most noticeable early signs. Many patients with Parkinson's disease experience despair, anxiety, and apathy, which can lead to cognitive and behavioral issues. Parkinson's disease dementia grows prevalent as the condition progresses. Parkinson's patients may also experience issues with their sleep and sensory systems. The disease's motor symptoms are caused by the loss of ce- -lls in the substantia nigra, a part of the midbrain, resulting in adopamine shortage. Alzheimer's Disease (AD) is a neurologicalillness that often begins slowly and progresses over time. It is theroot cause of 60–70% of dementia cases. The most frequent initialsymptom is trouble recalling recent events. Language impairments,disorientation (including easily getting lost), mood changes, loss ofmotivation, self-neglect, and behavioral concerns can all occur asthe condition progresses. As a person's health deteriorates, theyfrequently retreat from family and society. Body functions graduallydeteriorate, eventually leading to death. Although the rate ofprogression varies, the average life expectancy after diagnosis isthree to nine years.