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While the nocebo effect and other unfavorable effects are less widely researched and probably underestimated, the placebo effect is becoming more and more recognized as a factor in therapeutic effects in clinical practice. The likelihood of nocebo effects may be potentially increased by several parts of historical models of care in the fields of chiropractic, osteopathy, and physiotherapy. To encourage study and spread awareness for the mitigation of such negative impacts, physicians, researchers, and educators are urged to think on such possibilities in this masterclass piece. This lecture provides a basic overview of the nocebo effect and the mechanics that underlie it. The history of chiropractic, osteopathy, and physiotherapy is then traced, with the argument that the patient's body has been and still is given too much attention.
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