Continuous versus intermittent paracentesis in severe ovarian hyperstimulation syndrome: A multicenter randomized clinical trial

Author(s): Ayman Shehata Dawood*, Mona Khaled Omar MD and Mohamed Ahmed Elsharawy MD

BACKGROUND: Ovarian a syndrome (OHSS) is the most dangerous complication of assisted reproductive technologies. The syndrome has 3 degrees mild, moderate and severe. The severe form is characterized by marked enlargement of ovaries and ascites. Fluid management in sever OHSS was the main purpose of all relevant studies.

OBJECTIVE: To detect the efficacy, safety, applicability and patient satisfaction for the continuous paracentesis method in relation to intermittent method in management of severe cases of OHSS.

PATIENTS and METHODS: Patients with severe OHSS (n=118) were allocated into 2 groups continuous paracentesis group I, and intermittent paracentesis group II.

RESULTS: The demographic and cycle characteristics were compared. There were significant differences between both groups as regard duration of hospitalization, symptom relief, time to complete drainage of ascites and patient satisfaction, where marvelous improvement of symptoms and clinical signs were noticed within 24 h in group of continuous paracentesis.

CONCLUSION: Continuous paracentesis proved effective and safe for cases with severe OHSS and shortened duration of hospitalizations and drugs used with immediate symptom relief.

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