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The quantitative assessment of coronary plaques using Coronary Computed Tomography (CT) angiography is the main point of the article. It discusses three major findings: First, with the use of state-of-the-art CT scanners, coronary CT angiography is an accurate imaging technique for analyzing plaque volume and tracking volume change, with the great inter-and intra-reader agreement. Second, when plaque volume assessment is performed by the same vendor, scan variability is modest, but when assessment is performed by separate vendors at baseline and follow-up scans, scan variability is over 30%. Finally, assessing non-calcified plaques necessitates a high sample size, especially when using diverse vendors.
