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Background: Over the last decade medical care for transgender youth has improved. Gonadotropin-Releasing-Hormone-Analogues (GnRHa) stop and delay puberty and can relieve the distress of Gender Dysphoria (GD). Only a few adolescents treated with GnRHa desist from GD, thus systematic and in-depth investigations are missing.
Case Presentation: A case of peri pubertal onset gender dysphoria (12.4 years) is presented. It illustrates the desistance from GD after a 15-month-treatment with GnRHa. The blocking of puberty lead to a reduction of GD, the process of gender identity development still continued, leading to a non-binary outcome.
Conclusion: This case report illustrates that after treatment with puberty blockers desistance from gender dysphoria can occur. Further, GnRHa do not “the ongoing process of gender identity formation in psychosexual development. Thus, puberty suppression is a reversible treatment option that can be seen as a meaningful step to prepare the readiness for partially irreversible gender-affirming hormone treatment.
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