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Diabetic neuropathy, a prominent consequence of diabetes mellitus, refers to a group of clinically varied nerve system abnormalities that can cause discomfort. Despite the fact that the number of individuals suffering from severe neuropathy is growing, no optimum therapeutic technique has yet been identified. Acupuncture is widely known for its capacity to alleviate many types of pain, and some studies have indicated its benefit on diabetes mellitus; nevertheless, its efficacy and underlying mechanism against diabetic neuropathy are still unclear. This study examined 10 and five research conducted in people and animals, respectively, and found that acupuncture effectively alleviated diabetic neuropathy. The most often utilised acupoints were ST36, BL13, BL20, SP6, and SP9.