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Human anatomy, the study of the structure of the human body, has intrigued scholars, scientists, and medical professionals for centuries. From the ancient civilizations’ rudimentary understanding to the modern, intricate knowledge base, the field has evolved significantly. This comprehensive review aims to delve into the depths of human anatomy, covering its historical development, major anatomical systems, and contemporary advancements. Through the exploration of anatomical structures, functions, and clinical relevance, this article offers insights into the complexity and beauty of the human form.