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Type 2 diabetes, the primary metabolic complication of obesity, has become a global epidemic, necessitating the development of fresh approaches to both treating and preventing the disease. While essential for treating obesity, a good diet and regular exercise are frequently insufficient. Pharmacotherapy can help with compliance maintenance, reducing obesity-related health concerns, and enhancing quality of life. In the last two decades, there has been a tremendous improvement in our understanding of the cerebral and peripheral mechanisms driving homeostatic and hedonic aspects of food intake. Obesity may result from an imbalance in one or more of these factors.
