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Gymnema sylvestre, an Indigenous medicinal plant native to India and S.E Asia, has attracted a lot of interest in recent years for its potential therapeutic benefits. The plant is abundant in bioactive substances, particularly gymnemic acids, and triterpene saponins that have a variety of pharmacological actions. It has been utilized for centuries in traditional Ayurveda medicine for its health benefits particularly in managing blood-sugar levels and supporting weight management. It can reduce blood sugar levels by several mechanisms, including increased insulin secretion, improvising insulin sensitivity, and inhibiting sugar absorption in the intestine. Additionally, Gymnema sylvestre has been reported to stimulate the regeneration of pancreatic beta-cells, which are responsible for insulin production, suggesting potential long-term benefits in managing diabetes. Gymnema sylvestre possesses antioxidant and anti-inflammatory properties. This critical review examines the pharmacological properties and therapeutic applications of Gymnema Sylvestre, highlighting its efficacy in managing various diseases. With the medicinal prowess of Gymnema sylvestre, home remedies offer diverse health benefits. Gurmar Tea, brewed from crushed leaves, has potential to regulate blood sugar, Gurmar Leaf Paste aids wound healing when applied topically. The Gurmar Vinegar Tonic, infused with apple cider vinegar, supports digestion. Gymnema Infused Oil, derived from carrier oils, soothes the skin. Notably, Gymnema Herbal curd, incorporating Gymnema leaf extracts, exhibits promising activity against liver cancer during fermentation. Embracing Gymnema in home remedies exemplifies its holistic healing applications. To summarize this article aims to provide insights into the medicinal potential and clinical relevance of Gymnema sylvestre in modern healthcare
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