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Ischemic heart disease (IHD) and stroke are the world’s biggest killers. The good news is that 80% of cardiovascular diseases can be prevented with healthy lifestyle habits. The most effective approach to improve this situation is the reduction of risk factors levels. Small positive shifts of risk factors, across a whole population consistently leads to greater reductions in disease burden than the huge investment to the new drugs and devices including invasive procedures. Concrete examples of daily menu, adequate exercise proposals and obesity management how to reach recommended risk factors levels are discussed.