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Immunotherapy has emerged as a transformative approach in cancer treatment, harnessing the body's immune system to target and eliminate cancer cells. This article provides a comprehensive overview of immunotherapy, including its mechanisms, types, and impact on cancer treatment. We explore key innovations such as checkpoint inhibitors, CAR-T cell therapy, and cancer vaccines, highlighting their successes and ongoing challenges. The article also examines the current landscape of immunotherapy research, recent advancements, and future directions. By understanding the principles and progress in immunotherapy, we can appreciate its potential to reshape cancer treatment and improve patient outcomes.