Metabolism in Cancer: Uncovering the Role of Metabolic Pathways in Tumor Growth

Author(s): Pascali Jennifer*

Cancer cells exhibit distinct metabolic alterations that enable their uncontrolled growth and survival. This review explores the intricate relationship between metabolism and cancer, focusing on how metabolic pathways are reprogrammed to support tumorigenesis. We examine key metabolic processes, including glycolysis, oxidative phosphorylation, and the pentose phosphate pathway, and their role in sustaining cancer cell proliferation and evading apoptosis. Additionally, we discuss the impact of oncogenes and tumor suppressor genes on metabolic adaptations, highlighting the therapeutic potential of targeting metabolic pathways to inhibit tumor growth. By integrating recent findings from metabolomics and cancer biology, this review provides a comprehensive overview of how metabolic reprogramming drives cancer progression and offers insights into novel strategies for cancer treatment.

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