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This case report examines the neuroanatomical correlates of motor deficits in a patient who sustained a traumatic brain injury (TBI). The patient presented with hemiparesis and impaired coordination following a motor vehicle accident. Neuroimaging studies, including computed tomography (CT) and magnetic resonance imaging (MRI), were performed to assess the extent of structural brain damage and identify the underlying neural substrates responsible for the motor deficits. The findings revealed lesions in the corticospinal tract, primary motor cortex, and basal ganglia, highlighting the importance of understanding the neuroanatomical basis of motor function in patients with TBI. The case report emphasizes the significance of accurate diagnosis and tailored rehabilitation strategies based on neuroanatomical principles for optimal patient outcomes.