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Nutritional cognitive neuroscience is a new multidisciplinary topic of study that tries to understand the influence of diet on cognition and brain health across the lifespan. Many components of nutrition, from whole meals to single nutrients, impact brain structure and function, and hence have substantial implications for understanding the nature of healthy brain ageing, according to research in this developing subject. The goal of this Focused Review is to look at current breakthroughs in nutritional cognitive neuroscience, with a focus on strategies for discovering food biom-arkers that predict healthy brain ageing. We propose anintegrated approach that advocates for the integration ofnutritional epidemiology and cognitive neuroscience research,including: (i) techniques for precisely characterizing nutritionalhealth based on nutrient biomarker patterns (ii) contemporarymeasures of brain health obtained from high-resolution MagneticResonance Imaging (MRI). Nutritional cognitive neuroscience willcontinue to expand our understanding of the positive effects of dieton the ageing brain by merging cutting-edge methodologies fromnutritional epidemiology and cognitive neuroscience.