Plasma cell: Advances in health and disease

A variety of conditions known as plasma cell dyscrasias include the monoclonal proliferation of lymphoplasmacytic cells in the bone marrow and, sporadically, the deposition of monoclonal immunoglobulins or their constituent parts in tissue. Multiple Myelo- -ma (MM), Waldenström's macroglobulinemia, and other uncommon ailments including Light-Chain Deposition Disease (LCDD) and Heavy-Chain Diseases (HCDs) are among the disorders. Light-chain amyloidosis is a plasma cell dyscrasia and is one of a set of tissue deposition illnesses referred to as amyloidosis. Asymptomatic laboratory abnormality monoclonal gammopathy of unclear significance may develop.