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Kalaf (chloasma) is a brown macular hyper-pigmentation with well-defined scalloped symmetrical margins on cheeks, nose, forehead, and chin. The peak incidence is reported in the patients of 30-50 years of age. According to Unani system of medicine, Ghaleez Saudavi Bukharat (thick melancholic vapours) ascend towards the face and gets trapped beneath the skin; the dominance of abnormal black bile (Galba-e-Sauda) in the skin and blood are also involved in the disease pathogenesis. Vast body of literature is available in Unani Medicine for the treatment of melasma. Ancient Unani physicians such as Abu-al-Qasim Zohravi, ZakariyaRazi, IbnSina, Mohammad bin Tabri, and Ajmal Khan have described medicinal plants used for its treatment. The present review paper strives to explain the potential role of Unani medicinal plants used in the treatment of Kalaf
