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BACKGROUND: Spermatogenesis is a complex process involving mitotic cell division, meiosis and the process of spermatogenesis. The regulation of spermatogenesis involves both endocrine and paracrine mechanisms. The endocrine stimulation of spermatogenesis involves both testosterone and luteinizing hormone, the latter acting through the intermediary testosterone, produced by the Leydig cells in the testis. INTRODUCTION: Radiations are in energy form that’s travelling through space in the form of waves. Cell phone radiation classified as a non-ionizing. Non-ionizing radiation refers to a variety of electromagnetic radiation. HORMONAL ASSAYS: Testosterone Assay and Luteinizing Hormone assay. RESULTS: Post-treatment with Curcuma amada 100 mg/kg, 200 mg/kg and 300 mg/kg body weight) significantly improved the levels of LH and testosterone hormonal levels. In the Radiation alone groups were observed the Decreases the above hormonal levels. The present study was conducted to evaluate the protective effect of Curcuma amada on male reproductive system of hormonal estimations like total testosterone and LH against mobile phone radiation induced infertility in male Wister albino rats.