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Congenital variations, which encompass a wide range of anatomical anomalies present at birth, can significantly impact an individual's health and quality of life. This review explores the various surgical approaches employed to correct these congenital variations across different organ systems, including cardiovascular, gastrointestinal, and musculoskeletal disorders. We analyze the evolution of surgical techniques, highlighting minimally invasive procedures that reduce patient recovery time and improve outcomes. The review also addresses the challenges associated with surgical corrections, including complications, the need for interdisciplinary care, and long-term follow-up. By synthesizing current literature and case studies, we aim to provide a comprehensive overview of the effectiveness of surgical interventions in managing congenital variations, emphasizing the importance of early diagnosis and tailored treatment strategies to enhance patient outcomes. This review serves as a valuable resource for healthcare professionals involved in the care of patients with congenital anomalies, fostering a deeper understanding of surgical options and their implications for clinical practice.