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The covid-19 disease caused by SARS-CoV-2, the COVID-19, virus results in most governments telling their people to stay at home. This lockdown may well lead to more problems from mental stress and economic failure than are caused by the disease. Eventually there will be a vaccine to eliminate SARS-CoV-2 but there will not be a return to normal because the accumulation of disruption will have created irreversible changes, some worse and some better than before.