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The study's objective is to highlight the issue of Functional Hypothalamic Amenorrhea while taking into consideration any underlying diseases, their treatments, diagnoses, and effects. 38 original and review publications about Functional Hypothalamic Amenorrhea were included after searching PubMed. The most frequent cause of secondary amenorrhea in women of reproductive age is Functional Hypothalamic Amenorrhea. It is a condition that may be reversed and is brought on by stress connected to rapid weight reduction, intensive activity, or traumatic situations. Hormonal factors, including reduced gonadotropin secretion, impaired pulsatile GnRH secretion in the hypothalamus, and altered hormonal activity of the ovaries, form the basis of Functional Hypothalamic Amenorrhea. This condition causes hypoestrogenism, which causes amenorrhea and anovulation by disrupting the menstrual cycle. Long-term hypoestrogenism can be extremely hazardous to overall health and have numerous negative short- and long-term effects. It is important to begin Functional Hypothalamic Amenorrhea treatment as soon as feasible, with a focus on lifestyle changes. Pharmacological therapy shouldn't be started till after that. Importantly, even though therapy is frequently prolonged, the majority of patients recover as a consequence. Patients can avoid a variety of harmful effects on their fertility, cardiovascular health, and bone health, as well as reduce mental morbidity, with effective therapy that is based on multidirectional action.
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