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The gastroduodenal artery emerges posterior and superior to the first part of the duodenum from the common hepatic artery. The lower boundary of the first part of the duodenum gives rise to the right gastroepiploic and superior pancreaticoduodenal arteries. During routine dissection, we reported a variation in the origin of the gastroduodenal artery (from the celiac trunk). Such type of arterial variations requires complete preoperative evaluation in various surgical procedures.