Page 10
November 04-05, 2019 | Tokyo, Japan
6
th
INTERNATIONAL CONFERENCE ON GLOBAL HEALTHCARE
WORLD CONGRESS ON CARDIAC NURSING AND CARDIOLOGY
&
Cardiac Nursing & Global Healthcare 2019
November 04-05, 2019
Current Research: Cardiology
Volume 06
Curr Res Cardiol, Volume 06
Volumetric overload shocks in the patho-etiology of the transurethral resection
prostatectomy syndrome and acute dilution hyponatraemia
T
he Transurethral Prostatectomy Syndrome (TURS) is defined as severe vascular hypotension reaction that complicates
endoscopic surgery as a result of massive irrigating fluid absorption causing severe acute dilution hyponatraemia (HN) of
<120 mmol/l. The vascular shock is usually mistaken for one of the recognized shocks and Volumetric Overload Shock type 1
(VOS1) is overlooked making Volumetric Overload Shock Type 2 (VOS2) unrecognizable. In adults VOS1 is induced by the
infusion of 3.5-5 litres of sodium-free fluids and is known as TURS or HN shock. VOS2 is induced by 12-14 litres of sodium-
based fluids and is known as the adult respiratory distress syndrome. The most effective treatment for VOS1 and VOS2 is
hypertonic sodium Therapy of 5%NaCl or 8.4% Sodium Bicarbonate. The literature on TURS is reviewed and the underlying
patho-etiology is discussed.
As Starling’s law for the capillary-interstitial fluid transfer, which underlies the principles of fluid therapy, proved wrong an
alternative mechanism was found by studying the hydrodynamics of the porous orifice (G) tube akin to capillary. Incorporating
the G tube in a chamber (C), representing the interstitial space surrounding a capillary, demonstrated a rapid dynamic magnetic
field-like fluid circulation between the C and G tube lumen. The G-C phenomenon is autonomous having both filtration and
absorption forces making a true replacement for Starling’s law in every tissue and organ of the body.
Biography
Ghanem was educated in Egypt and qualified in 1968, Mansoura University, Egypt. He gained postgraduate experience in UK where he
was promoted in posts up to the consultant level. He practiced as consultant Urologist in UK, Saudi Arabia and Egypt. During his career
he reported over 60 articles. He discovered two new types of vascular shocks, proved that one physiological law is wrong and provided an
alternative. He resolved the puzzles of 3 clinical syndromes; TURP syndrome, the LPHS andARDS. He is now on an editorial board member
of many journals while he is happily retired in Egypt.
e
:
anmghanem1@gmail.comAhmed N Ghanem
Mansoura University, Egypt
Figure: shows diagram of the porous orifice (G) tube enclosed in chamber (C) based on several
photographs demonstrating the magnetic field-like G-C circulation phenomenon. The proximal
inflow (arterial) pressure (1) pushes fluid through the orifice (2) creating fluid jet in the lumen
of the G tube. The fluid jet creates negative side pressure gradient causing suction maximal over
the proximal half of the G tube near the inlet (3) that sucks fluid into lumen. The side pressure
gradient turns positive pushing fluid out of lumen over the distal half maximally near the outlet (4).
Thus the fluid around G tube inside C moves in magnetic field-like fluid circulation (5) taking an
opposite direction to lumen flow of G. tube. The inflow (arterial) pressure (1) and orifice (2) induce
the negative side pressure energy creating the dynamic G-C circulation phenomenon that is rapid,
autonomous and efficient in moving fluid out from the G tube lumen at (4), irrigating C at (5),
then sucking it back again at (3), maintaining net negative energy pressure (7) inside C. The distal
outflow (venous) pressure (6) enhances outflow at (4) and its elevation may turn the negative energy
pressure (7) inside C into positive, increasing volume and pressure inside C chamber.