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Page 38
3
rd
International Congress on
Annual Summit on
October 02-03, 2017 Atlanta,USA
&
Microbiology and Pharmaceutical Microbiology
Sexual & Reproductive Health
Journal of sexual and Reproductive medicine | Volume.1, Issue.2
The effect of vitamin C, vitamin E, zinc, selenium and coenzyme Q10 in infertile men
with idiopathic oligoasthenozoopsermia
Ahmed T Alahmar
and
MBChB, MSc
1
College of Pharmacy, University of Babylon, Iraq
Background:
Accumulating evidence suggests that oxidative stress plays an important role in the development
of male infertility and recently antioxidants have been tried to treat men with idiopathic infertility.
Objective:
To assess the effect of treatment with vitamin C, vitamin E, zinc, selenium and coenzyme Q10 on
seminal fluid parameters in infertile men with idiopathic oligoasthenozoospermia.
Materials and methods:
A prospective randomised trial was conducted on thirty-two infertile men with
idiopathic oligoasthenozoospmia who received a daily supplement of one caplet containing vitamin C (90 mg/
day), vitamin E (15 mg/day), coenzyme Q10 (4 mg/day), selenium (30 µg/day) and zinc (5 mg/day) for three
months. Semen analysis was performed at baseline and three months after treatment using WHO 2010 guidelines.
Results:
Significant improvement in sperm concentration was observed after combination therapy (9.13±4.29 vs.
11.3±6.05 *106/ml, P <0.05). Sperm progressive motility (18.1±8.68 vs. 24.6±10.2 %, P<0.01) and total motility
(28.4±8.71 vs. 34.4±11.7 %, P<0.01) also increased significantly following treatment. No change, however, was
observed in semen volume or the proportion of sperms with normal morphology.
Conclusion:
The combination of vitamin C, vitamin E, zinc, selenium and coenzyme Q10 can significantly
improve sperm concentration and motility infertile men with idiopathic oligoasthenozoospermioa which could
be attributed to their synergistic antioxidant action..
ahmed.t.alahmar@gmail.com