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3rd International Conference on
Health Care and
Health Management
Joint Event
&
November 04-05, 2019 | Prague, Czech Republic
6th International Conference on
Neuroscience and
Neurological Disorders
Journal of Neurology and Clinical Neuroscience | Volume 3
Inflammation in psychiatric disorders and what to do about it?
Bc Vojtěch Hlaváček
Academy of Science of Czech Republic, Czechia
Statement of the Problem: Psychiatric disorders are
becoming an increasing problem and possess a socio-
economic burden on societies worldwide. There has been
an association between inflammation and psychiatric
disorders for some time now, but the causal relationships
and mechanisms are not fully understood yet. Better
understanding of those mechanisms could help us in dividing
patients into different mechanistic subtypes which could
react differently to a treatment. That way we could prescribe
the most effective treatment depending on the mechanism
involved. Inflammation is sensitizing an individual to react
in more pro-inflammatory fashion to a stressor leading to
chronically inflamed states. This is something that we can
observe in an array of mechanisms, which creates many
positive inflammatory feedback loops. Those feedback loops
are very hard to interrupt, because they reinforce each other,
plus the immune system is overreacting to subsequent
stressor creating a vicious cycle. This could potentially lead to
development of neurodegenerative diseases. As it turns out,
physical activity acts on several of thosemechanisms involved
in inflammatory feedback loops at the same time, making it
an ideal prevention/treatment candidate. It plays a huge role
in regulation of inflammation in anti-inflammatory manner
and might be one of the ways to prevent and treat patients
with psychiatric disorders such as major depressive disorder
as well as neurodegenerative diseases. This thesis is going
to explore relationship between inflammation and mental
health. Possible causal relationships between inflammation
and psychiatric disorders will be discussed. Mechanisms
involved in inflammation regulation, effects of physical
activity and inflammation induced pathology observed in
psychiatric disorders will be described.
Speaker Biography
Bc Vojtěch Hlaváček is a passionate student of neuroscience focusing on
inflammation and development of psychiatric disorders. He is focusing on
improving our daily experience with reality, because that is all we have.
Because of that, he is creating a Czech podcast Brain We Are CZ, where
he shares his expertise and original concepts that he came up based in
principles from neuroscience.
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