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September 02-03, 2019 | Vienna, Austria
Volume 3 | ISSSN: 2632-251X
Nursing Forum 2019 & Rheumatology 2019
September 02-03, 2019
Journal name: Journal of Nursing Research and Practice
WORLD NURSING FORUM
RHEUMATOLOGY & TRAUMA CARE
13
th
International Conference on
&
J Nurs Res Pract, Volume 3
Influence of age, ethnicity and life span issues in abnormal thrombosis
T
here is a direct relationship between unusual thrombotic episodes and deficient natural anticoagulants. Thrombotic episodes
are the result of a genetic and environmental factors as well as an imbalance between procoagulant and anticoagulant factors.
Such imbalance cause either hemophilia or thrombophilia. Thrombophilia is precipitated by various causes, predominantly
genetic factors. Deficiency of Protein C (PC) and Protein S (PS) is the principal etiopathology for this anomaly (Hernandez,
Zamora, 2016). The prevalence of PS deficiency among Caucasians is 0.03%-0.13%where as it is 1-2% inAsian population. The
common hereditary type of thrombophilia seen in Caucasian population is Factor V Leiden and Prothrombin mutation that are
not common in Asians. Whereas, deficiencies related to natural anticoagulants are higher in Asians (Satpanich & Rojnuckarin,
2019). Among Asians, the Japanese have a higher incidence related to a special gene mutation called PS Tokushima manifested
as a qualitative PS deficiency. In addition to the race and ethnicity, age and gender also influence PS levels. PS if found high as
the age advances, and PS level is relatively high in males compared to females. During the third trimester of pregnancy, there is
a transient reduction in PS (Caroll et al, 2017). Abnormal venous or arterial thrombosis found in unusual sites in relatively young
may be due the Protein C and S deficiency. Such thrombotic episodes cause morbidity and mortality and therefore it is important
for to understand the anomaly. The significance of Protein S (PS), Protein C (PC) and other factors will be introduced through
discussion of multiple cases. Natural anticoagulants’ deficiency, types, normal levels, lab diagnosis, thrombosis management,
prevention and long-term care will be included in the presentation.
Biography
Elizabeth Simon, R.N., A.N.P.-B.C., Ph.D., is a professor of nursing. Prior to coming to NYIT in 2018, she was a professor of nursing and
dean of the School of Nursing at Nyack College. She also previously served as faculty and post-master’s nursing education coordinator at
Hunter-Bellevue School Nursing at Hunter College and as a critical care nursing consultant for Corporate Nursing Services of NYC Health
and Hospitals Corporation (NYCHHC).
Simon has more than 25 years of nursing education experience and more than 30 years of clinical experience. She is a board certified adult
health nurse practitioner who has authored, reviewed, or edited books on critical care nursing; book chapters on transcultural issues; and
a book on non-communicable diseases. She has published several articles in peer reviewed journals and periodicals and has presented
at various national and international forums. Simon’s academic degrees include
B.Sc. (N.) from the College of Nursing, Christian Medical
College, Ludhiana, Punjab University, India; M.S. in Critical Care Nursing from School of Nursing, Columbia University; Ed.M. in Nursing
Education from Teachers College; M.S. in Adult Health Nurse Practitioner from Hunter College; and Ph.D. in higher education from Walden
University. Aspecialist in nursing education, Simon was a Fulbright Scholar in India, where she taught critical care nursing during the 2015-16
academic year.
esimon03@nyit.eduElizabeth Simon
New York Institute of Technology, USA