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December 09-10, 2019 | Barcelona, Spain
Nursing Practice 2019 & Neonatology 2019
December 09-10, 2019
Nursing and Nursing Practice Neonatology and Perinatology
7
th
Global Experts Meeting on
4
th
World Congress on
ISSN: 2632-251X | Volume 3
Journal of Nursing Research and Practice
J Nurs Res Pract, Volume 3
Necrotizing enterocolitis in a Preterm Infant Newborn & role of feeding. An Update
Said Moustafa M, Eldeib
and
Amr I M Hawal
NMC Health Care Group, UAE
Statement of the Problem:
It’s a clinical case presentation of a male Preterm infant Newborn (+31 wks) who was delivered
in our hospital & transferred to our NICU because of Prematurity, VLBW& need to respiratory support. Baby shortly undergo
Necrotizing Enterocolitis (NEC) on 5th day of life shortly after start of expressed milk feeding! Which was early detected by
use of Near Infrared Abdominal spectroscopy (NIRS). Baby was deteriorated clinically in a couple of hours & undergo
intestinal perforation with peritonitis , So, Abdominal exploration surgery with intestinal resection & end – to end anastomosis
was done urgently. Baby improved gradually & early feedings was started & gradually increased up to full feedings with use of
Human Fortified Milk (HMF) & probiotics, Prebiotics.
Findings:
The Study stated the evidence-based Feeding Strategies guidelines for necrotizing enterocolitis (NEC) among
very low birth weight infants & Role of trophic feedings, Probiotics, Prebiotics & micronutrients in Prophylaxis, Prevention
& Management of NEC.
Recommendations:
1)-Prematurity is the single greatest risk factor for NEC & avoidance of premature birth is the best way
to prevent NEC. 2)-The role of feeding in the pathogenesis of NEC is uncertain, but it seems prudent to use breast milk (when
available) and advance feedings slowly and cautiously. 3)-NEC is one of the leading causes of mortality, and the most common
reason for emergent GI surgery in newborns. 4)-NEC remains a major unsolved medical challenge, for which no specific
therapy exists, and its pathogenesis remains controversial. 5)-Abetter understanding of the pathophysiology will offer new and
innovative therapeutic approaches and future studies should be focused on the roles of the epithelial barrier, innate immunity
and microbiota in this disorder. 6)-Bioinformatics modeling is a new emerging strategy aimed at understanding the dynamics of
various inflammatory markers and their application in early diagnosis and treatment.